Washington, 1984, pp 643–828, Keefer LK. IARC Scientific Publicaions No 14, 1976, pp 425–428, Blevins RD, Lijinsky W, Regan JD: Nitrosated methylcarbamate insecticides: Effect on the DNA of human cells. Cancer Lett 12: 99–103, 1981, Althoff J, Wilson R, Cardesa A, Pour P: Comparative studies of neoplastic response to a single dose of nitroso compounds. J Cancer Res Clin Oncol 112: 221–228, 1986, Lijinsky W, Reuber MD, Blackwell B-N: Carcinogenicity of nitrosotrialkylureas in Fischer rats. J Natl Cancer Inst 73: 1215–1218, 1984, Lijinsky W, Singer GM, Kovatch RM: Similar carcinogenic effect in rats of 1-ethyl-1-nitroso-3-hydroxyethylurea and 1-hydroxyethyl-1-nitroso-3-ethylurea. The effect of N-nitrosopiperidine and N-nitrosomorpholine in Syrian golden hamsters. &�滇9�(�n�o���B1�N�mg��l�l�Y�̯۸��!H�%�����o +mY3
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J Natl Cancer Inst 58: 429–432, 1977, Lijinsky W, Reuber MD: Comparison of carcinogenesis by two isomers of nitroso-2,6-dimethylmorpholine. Immediate online access to all issues from 2019. Carcinogenesis 7: 1335–1337, 1986, Okada M: Comparative metabolism of N-nitrosamines in relation to their organ and species specificity. Fodor CH: Facile hydrogen isotope exchange as evidence for an α-nitrosamaine carbanion. Epub 2011 Dec 27. J Cancer Res Clin Oncol 109: 1–4, 1985, Cardy RH, Lijinsky W: Comparison of the carcinogenic effects of five nitrosamines in guinea pigs. GANN Monogr Cancer Res 17: 161–176, 1975, BRI-Basic Research Program, Chemical Carcinogenesis Program, NCI-Frederick Cancer Research Facility, 21701, Frederick, MD, USA, You can also search for this author in 1982, Lijinsky W, Deuterium isotope effects in carcinogenesis by N-nitroso compounds and related carcinogens. Z Krebsforsh 89: 215–219, 1977, Lijinsky W, Reuber MD, Davies TS, Riggs CW: Doseresponse studies with nitrosoheptamethyleneimine and its alpha deuterium labeled derivative in F344 rats. ]�2�$�t�o�a����|��m����E� � Cancer Res 35: 1270–1273, 1975, Reznik G, Mohr U, Lijinsky W: Carcinogenic effect of N-nitroso-2.6-dimethylmorpholine in Syrian golden hamsters. In all the studies doses of the various compounds, equimolar to the extent that was possible, are administered orally. Carcinogenesis 1: 501–503, 1980, Lijinsky W, Reuber MD: Comparative carcinogenicity of two isomers of dimethylnitrosomorpholine in guinea pigs. Cancer Lett 19: 207–213, 1983, Lijinsky W, Reuber MD, Davies TC, Riggs CW: Doseresponse studies with nitroso-1,2,3,6-tetrahydropyridine and dinitrosohomopiperazine. k��!�~9Ԛ%��.1��~��FO! J Natl Cancer Inst 68: 681–684, 1982. Cancer Res 40: 1879–1884, 1980, White IMH, Smith AG, Farmer PB: Formation of N-alkylated protoporphyrin IX in the livers of mice after diethylnitrosamine treatment. N-Methyl-N-nitrosourea as a mammary carcinogenic agent. Cancer Res submitted. While most directly acting N-nitroso compounds and those requiring metabolic activation are mutagenic with appropriate activation and seem to alkylate DNA in vivo, there are exceptions. Inactivity of N-nitroso-bis-(2,2,2-trifluoroethyl)amine in carcinogenicity and mutagenicity tests. Z Krebsforsch 92: 221–225, 1978, Pour P, Gingell R, Langenbach R, Nagel D, Grandjcan C, Lawson T, Salmasi S: Carcinogenicity of N-(nitrosomethyl-2-oxopropyl)amine in Syrian hamsters. Cancer Lett 16: 281–286, 1982, Mohr U, Reznik G, Emminger E, Lijinsky W: Induction of pancreatic duct carcinomas in the Syrian golden hamster with 2,6-dimethylnitrosomorpholine. GANN 65: 69–73, 1974, Ketkar MB, Althoff J, Lijinsky W: The carcinogenic effect of nitrosomethyldodecylamine in European hamsters. `R Lb1dmwiA ��B����DŽf�2Ƨ�'8R�*�2��ޘ_��� q���4��q�A�dR��,�q�����}���
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84, 49–54, 1987, Lijinsky W, Reuber MD, Davies TS, Saavedra JE, Riggs CW: Dose-esponse studies in carcinogeesis by nitrosomethyl-2-phenylethylamine in rats and the effect of deuterium. (eds) Genotoxicology of N-Nitroso Compounds. Effects of N′-nitrosonornicotine and N′-nitrosoanabasine in rats. NLM Biomater Res. Proc Natl Acad Sci USA 78: 6489–6493, 1981, Preussmann R, Ivankovic S, Lanschütz C, Gimmy J, Flohr E, Griesbach U: Carcinogenic activity of 13 aryldialkyl triazenes in BD-rats. Cancer Res 35: 2123–2125. h�b```f`` H��T�r�0}�W�2CT�n�� m��2�fxH��:j���v��H���0�x>�@��RB�U Subscription will auto renew annually. ����Ş�Ξo;&�h� ���\���x�0p�O 0
Fd Cosmet Toxicol 20: 393–399. 41, 625–631, 1982, Lijinsky W: Significance of N-nitroso compounds as environmental carcinogens. GANN 67: 771–772, 1976, Althoff J, Lijinsky W: Urinary bladder neoplasms in Syrian hamsters after administration of N-nitroso-N-methyl-N-dodecylamine. endstream
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Carcinogenesis 4: 157–160, 1983, Lijinsky W, Taylor HW: The change in carcinogenic effectiveness of some cyclic nitrosamines at different doses. Carcinogenesis 6: 641–643, 1985, Goth R, Rajewsky MF: Persistence of O6-ethylguanine in rat brain DNA. GANN 64: 193–196, 1973, Lijinsky W, Kovatch RM, Singer SS: Carcinogenesis in F344 rats by nitrosohydroxyalkylchloroethylureas. Carcinogenesis 2: 753–756, 1981, Lijinsky W, Kovatch RM, Knutsen GL: Carcinogenesis by nitrosomorpholines, nitrosooxazolidines and nitrosoazetidine given by gavage to Syrian golden hamsters. J Natl Canc Inst 51 299–302, 1973, Lijinsky W, Reuber M: Carcinogenicity in rats of nitrosomethylethylamies labeled with deuterium in several positions. In: O'Neill IK, Von Borstel RC, Miller CT, Long J. Bartsch H (eds) N-Nitroso Compounds: Occurrence. :�k�� +�J-�Zݳ�C��]m�[_KF�gqDI9B>^���
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